Collection of scientific works Nanosystems, nanomaterials, nanotechnologies Year 2024 Volume 22, Issue 3
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D.N. NOZDRENKO, O.P. MOTUZUK, O.V. DOLHOPOLOV, ².V. PAMPUHA, and K.I. BOGUTSKA

C60 Fullerene Contributes to the Restoration of Precise Positioning of the muscle soleus After Achillotomy-Induced Atrophy
527–534 (2024)

PACS numbers: 81.16.Fg, 87.16.dp, 87.16.dr, 87.19.Ff, 87.19.lt, 87.19.R-, 87.19.xn, 87.85.G-

The effect of C60-fullerene aqueous solution (with daily oral dose of 1 mg/kg) on the restoration of hysteresis effects of muscle contraction responsible for the correction of the precise positioning of joints in the development of atrophic changes associated with long-term immobilisation is investigated. A clinical model of Achilles-tendon rupture is used to study the development of muscle atrophy. Muscle-contraction parameters are recorded on the 15th, 30th, and 45th day after the initiation of atrophy. The obtained results confirm the effectiveness of C60-fullerenes’ influence on the functions of the antioxidant system in the development of pathological processes

KEY WORDS: muscle soleus, atrophy, C60 fullerene, biomechanical parameters

DOI:  https://doi.org/10.15407/nnn.22.03.527

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