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MOHAMMAD DARWISH ORABI, WARDA KHALIL, KHALED ALZOBAR, and
JOMAA MERZA
Synthesis and Characterization of the New
Imidazole-Derivative Salts’ Nanoparticles and Studying of Its Biological Activity
501–516 (2024)
PACS numbers: 81.16.Be, 87.18.-h, 87.19.X-, 87.64.Ee, 87.64.kj, 87.64.km, 87.85.Rs
Heterocyclic compounds have great importance in the medical and industrial fields.
Imidazole compounds and salts are the most widespread and effective of these compounds. Therefore, in this
research, we prepare a number of mono- and di-substituted derivatives of imidazole and its salts. The
prepared compounds are characterized using 1H-NMR, 13C-NMR, SEM, and IR techniques. In addition, the
biological activity against Escherichia coli and Staphylococcus aureus bacteria is studied for the prepared
compounds. As revealed, the prepared salts are more biologically effective
KEY WORDS: imidazole derivatives, heterocyclic compounds, imidazole salts, pharmacological applications, biological activity
DOI: https://doi.org/10.15407/nnn.22.02.501
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