 |
|||||||||
 |
Year 2021 Volume 19, Issue 4 |
|
|||||||
|
|||||||||
Issues/2021/vol. 19 /Issue 4 |
O. V. Savvova, O. I. Fesenko, O. V. Babich, Î. À. Nikolchenkî, H. K. Voronov, and Yu. O. Smyrnova
«Features of Mineralization of Hydroxyapatite on the Surface of Calcium-Silicophosphate Glass-Ceramic Materials in vivo
»
0953–0965 (2021)
PACS numbers: 68.35.-p, 68.37.Hk, 81.05.Pj, 87.19.rd, 87.85.J-, 87.85.Lf, 87.85.Qr
The features of mineralization of hydroxyapatite (HAp) on the surface of calcium-silicophosphate glass-ceramic materials in vivo are analysed. It is found that the implantation of biomaterials based on BS-11 and ASZ-5 bioactive glass-ceramic materials characterized by a strengthened structure and an adjustable level of resorption implements the chemical and biochemical mechanisms of formation of the apatite-like layer. The peculiarities of compositions and technologies for obtaining bioactive glass–ceramic materials for replacement of bone defects are analysed. The conditions for the formation of an apatite-like layer in vivo on the surface of glass-ceramic materials are established. These ones include crystallization process of fine-dispersed HAp, ensuring the reactivity of glass-ceramic materials due to destruction of them, initiation of the nucleation of non-stoichiometric HAp on the surface of materials. As determined, the stimulation of the adsorption process of proteins on the surface of the ASZ-5 and BS-11 glass-ceramic materials is realized by ensuring the values of the surface microroughness index Ra = 2.6 and 6.0 μm and the surface free energy of 51.5 and 74.6 MJ/m2, respectively. For the developed glass-ceramic materials based on calcium-silicophosphate glasses, the formation of a sitallized structure under conditions of low-temperature heat treatment makes it possible to provide their operational properties close to those for bone cortical tissue (K1C = 2.44 and 2.8 MPà·m1/2, HV = 7800 and 3800 ÌPà, σñompr = 160 ÌPà). This fact allows us to consider them as promising when creating implants, which can be used to replace the statically and dynamically loaded areas of bone tissue in orthopaedics and maxillofacial surgery. This one, together with the shortened periods of resorption and mineralization of bone tissue, will increase the efficiency of prosthetics by halving the rehabilitation period for patients and avoiding the necessity for repeated operations.
Key words: glass-ceramic materials, biomaterials, in vivo, apatite-like layer, bone tissue
https://doi.org/10.15407/nnn.19.04.953
References
1. D. D. Kiradziyska and R. D. Mantcheva, Folia Med., 61, No. 1: 34 (2019); doi:10.2478/folmed-2018-0038
2. H. Owara, K. Hoshi, and N. Amizuka, J. Oral Biosci., 50, No. 1: 1 (2008); https://doi.org/10.1016/S1349-0079(08)80014-X
3. V. I. Sevast’yanov, Biosovmestimost’ [Biocompatibility] (Moscow: IC VNIIGS: 1999) (in Russian).
4. W. Elshahawy, Advances in Ceramics—Electric and Magnetic Ceramics, Bioceramics, Ceramics and Environment. Ch. Biocompatibility (Ed. C. Sikalidis) (Rijeka, Croatia: InTech: 2011); doi:10.5772/18475
5. Ch. Sato, D. Yamazato, M. Sato, H. Takeshima, N. Memtily, Y. Hatano, T. Tsukuba, and E. Sakai, Sci. Rep., 9: 1 (2019); doi:10.1038/s41598-019-43608-6
6. K. Ravindranadh, Int. J. Chem. Sci, 14, No. 3: 1339 (2016).
7. O. V. Savvova and O. I. Fesenko, Nanosistemi, Nanomateriali, Nanotehnologii, 15, No. 4: 649 (2017) (in Ukrainian); https://doi.org/10.15407/nnn.15.04.0649
8. O. V. Savvova, O. V. Babich, and G.N. Shadrina, Functional Materials, 21, No. 4: 421 (2014); http://dx.doi.org/10.15407/fm21.04.421
9. O. Savvova, O. Babich, M. Kuriakin, A. Grivtsova, and V. Topchiy, Functional Materials, 24, No. 2: 109 (2017); https://doi.org/10.15407/fm24.02.311
10. O. V. Savvova, V. M. Shimon, O. V. Babich, and M. V. Shimon, Functional Materials, 27, No. 4: 767 (2020); https://doi.org/10.15407/fm27.04.767
11. C. C. Barry, Ceramic Materials: Science and Engineering (Ed. Norton M. Grant) (Berlin: Springer: 2007).
12. V. V. Lashneva, A. V. Shevchenko, and E. V. Dudnik, Glass and Ceramics, 66, Nos. 3–4: 140 (2009); https://doi.org/10.1007/s10717-009-9148-0.
 This article is licensed under the Creative Commons Attribution-NoDerivatives 4.0 International License ©2003—2021 NANOSISTEMI, NANOMATERIALI, NANOTEHNOLOGII G. V. Kurdyumov Institute for Metal Physics of the National Academy of Sciences of Ukraine. E-mail: tatar@imp.kiev.ua Phones and address of the editorial office About the collection User agreement |