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О. Н. Мусская, А. И. Кулак, В. К. Крутько, Л. А. Лесникович, С. А. Уласевич, Л. Ф. Суходуб
«Твердеющие композиции на основе нанокристаллических фосфатов кальция и биосовместимых полимеров»
781–790 (2013)

PACS numbers: 62.23.Pq, 81.07.Pr, 82.35.Np, 82.70.Dd, 83.60.-a, 87.85.jj, 87.85.Rs

New composite calcium phosphate cements with 13–55% porosity, 1–60 minute setting time, and 0,1–8,7 МPа static strength on the base of nanocrystalline calcium phosphates (hydroxyapatite, tricalcium phosphate) and biocompatible polymers (sodium carboxymethyl cellulose, polyvinyl alcohol) are obtained. The influences of hydroxyapatite gel concentration, temperature and polymer admixture on the setting time and static strength of the composite calcium phosphate cements are studied. Biocompatibility and toxicological safety of the calcium phosphate cements are been demonstrated by preclinical trials in vivo. The cements are prospective for practical application as a biocompatible component of coatings on titanium implants for neurosurgery and orthopaedics, and as self-harding composites.