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V. V. Kiroshka, N. V. Repin, I. I. Samchenko, V. M. Nadutov, A. O. Perekos, and V. Z. Voynash
«Biological Compatibility of Polyol Synthesized Magnetite Nanoparticles»
415–422 (2012)

PACS numbers: 47.63.mh, 75.75.Cd, 81.16.Be, 87.64.Bx, 87.64.Ee, 87.85.jj, 87.85.Rs

The structural and magnetic properties of magnetite nanopowder obtained with polyol synthesis and its cytotoxicity at interaction with the cell culture are studied in a given work. As shown by x-ray diffraction method, the synthesized powder has spinel structure with the lattice parameter of 0.8393 nm. High dispersion of powder with the particle sizes of 10 nm and rather low aggregation are revealed in TEM studies. As found, there is 100% preservation of cell viability during 2 hours incubation for all the studied concentrations of magnetite. A reverse dependence of the cell viability rate on used concentration of nanoparticles with increasing the exposure time up to 24 hours is revealed; moreover, the decrease in cell viability by 50% is revealed at the concentration of the particles of 0.6 mg/ml Fe3O.