Âûïóñêè

 / 

2009

 / 

òîì 7 / 

âûïóñê 1

 



Ñêà÷àòü ïîëíóþ âåðñèþ ñòàòüè (â PDF ôîðìàòå)

A. I. RAYCHENKO, N. F. KUSHCHEVSKAYA, E. V. DEREVYANKO, and V. V. OGORODNIKOV
«On Parameters of Magnetic Nanosuspensions Intended for Treatment in Oncology»
255–261 (2009)

PACS numbers: 75.50.Tt, 81.16.Fg, 82.70.Kj, 83.80.Hj, 87.19.xj, 87.50.Ct, 87.85.Rs

The magnetic field (MF) can influence a tumour ambiguously. The understanding of the MF role in cancer therapy can be achieved by the research of changing of cancer-cells’ number, for instance, by the mathematical model ‘predator–victim’, i.e. by the analysis of fight of two populations—lymphocytes (‘predators’) and cancer cells (‘victims’). If the peculiarities of this ‘immune supervision’ can be expressed in connection with parameters, which quantitatively reflect the real biophysical terms, then it will be possible to elaborate correct treatment strategy. As revealed, the MF excites the following processes in cancer organism: strengthening of the tissue breathing, oxidizing phosphorylation, change of microcirculation and glio-neuronal relations in the hypothalamus, increase of free-radicals’ number, destructive changes of membranes and kernels in tumour cells, violation of synthetic activity and energy deficit of cells, increase of dystrophy, necrosis. However, such an influence of the MF is possible that results in suppression of cancer-resistance of organism. The effective method consists in using of suspension of fine ferromagnetic particles in liquids. Such a ‘magnetic suspension’ being entered in the circulatory system or lymphosystem, which penetrate a tumour, should provide the influence from side of the MF sources to the cancer cells by the most ‘contact’ mode. The experiments in vivo showed: average live span of rats with Guerin’s carcinoma (intact control) is equal to 19.3 days; the corresponding quantity after exertion of the Fe particles (50–250 nm) is equal to 30 days.

©2003—2021 NANOSISTEMI, NANOMATERIALI, NANOTEHNOLOGII G. V. Kurdyumov Institute for Metal Physics of the National Academy of Sciences of Ukraine.
E-mail: tatar@imp.kiev.ua Phones and address of the editorial office About the collection User agreement