Collection of scientific works Nanosystems, nanomaterials, nanotechnologies
Year 2026 Volume 24, Issue 2
Download the full version of the article (PDF, In Ukrainian / Українською) Open Access

V. L. DEMCHENKO1, N. P. RYBALCHENKO2, M. V. IURZHENKO1, D. V. KUNYTSKYI1, A. I. MARYNIN3, V. B. DOLGOSHEY4, V. O. OVSYANKINA4, T. V. RYBALCHENKO5, and O. A. BURYANOV6

1E. O. Paton Institute of Electric Welding, N.A.S. of Ukraine, 11, Kazymyr Malevych Str., UA-03150 Kyiv, Ukraine
2D. K. Zabolotny Institute of Microbiology and Virology, N.A.S. of Ukraine, 154, Academician Zabolotny Str., UA-03143 Kyiv, Ukraine
3National University of Food Technologies, 68, Volodymyrs’ka, Str., UA-01601 Kyiv, Ukraine
4National Technical University of Ukraine ‘Igor Sikorsky Kyiv Polytechnic Institute’, 37, Beresteiskyi Ave., UA-03056 Kyiv, Ukraine
5Educational and Scientific Centre ‘Institute of Biology and Medicine’, Taras Shevchenko National University of Kyiv, 2, Academician Glushkov Ave., UA-03022 Kyiv, Ukraine
6Bogomolets National Medical University, 27, Bulvarno-Kudryavs’ka Str., UA-01601 Kyiv, Ukraine

Structure and Properties of Polymeric Cryogel Materials Based on Polyvinyl Alcohol and Ag2O Nanoparticles

637–648 (2026)

PACS numbers: 61.05.cf, 61.25.hp, 62.23.Pq, 81.40.Jj, 82.35.Np, 83.80.Hj, 87.85.Rs

Received 23 January, 2026; in revised form, 22 May, 2026

Polymeric cryogel materials based on polyvinyl alcohol, polyglutamic or hyaluronic acid (HA) and Ag2O nanoparticles are formed. Studies of cryogel nanocomposite materials by the method of wide-angle x-ray scattering show that during the formation of samples, silver ions are reduced in the polymer systems PVA–Ag+–HA with the formation of Ag2O nanoparticles. As found, PVA–3 wt.% HA samples have the highest water-absorption values. As shown, the tensile strength and relative deformation of samples based on polyvinyl alcohol and hyaluronic acid improve with an increase in the concentration of Ag2O nanoparticles to 0.5 wt.%. The formed polymer cryogels exhibit antimicrobial activity against opportunistic pathogenic microorganisms: S. aureus, S. epidermidis, E. coli, P. aeruginosa.

KEY WORDS: hyaluronic acid, polyvinyl alcohol, cryogel materials, Ag2O nanoparticles, structure, morphology, mechanical strength, antimicrobial activity

DOI: https://doi.org/10.15407/nnn.24.02.0637

Citation:
V. L. Demchenko, N. P. Rybalchenko, M. V. Iurzhenko, D. V. Kunytskyi, A. I. Marynin, V. B. Dolgoshey, V. O. Ovsyankina, T. V. Rybalchenko, and O. A. Buryanov, Structure and Properties of Polymeric Cryogel Materials Based on Polyvinyl Alcohol and Ag2O Nanoparticles, Nanosistemi, Nanomateriali, Nanotehnologii, 24, No. 2: 637–648 (2026); https://doi.org/10.15407/nnn.24.02.0637

Funding / Acknowledgments:
The work was carried out with the financial support of the grant of the National Research Foundation of Ukraine ‘Development of Biopolymer Nanocomposite Materials for Stimulating the Regeneration of Living Tissues and Wound Healing’ (application ID 2023.05/0009).

REFERENCES
  1. V. L. Demchenko, S. M. Kobylinskyi, S.V. Riabov, V. I. Shtompel, M. V. Iurzhenko, and N. P. Rybalchenko, Applied Nanoscience, 10, No. 12: 5409 (2020); https://doi.org/10.1007/s13204-020-01368-0
  2. V. L. Demchenko, V. I. Shtompel’, and S. V. Riabov, Polymer Science, A57: 635 (2015); https://doi.org/10.1134/S0965545X15050065
  3. Valeriy Demchenko, Sergii Riabov and Volodymyr Shtompel’, Nanoscale Research Letters, 12: Article No. 235 (2017); https://doi.org/10.1186/s11671-017-1967-2
  4. V. Demchenko, V. Shtompel’, S. Riabov, and E. Lysenkov, Nanoscale Research Letters, 10: 479 (2015); https://doi.org/10.1186/s11671-015-1181-z
  5. W. Sikorska, M. Zięba, M. Musioł, M. Kowalczuk, H. Janeczek, P. Chaber, O. Masiuchok, V. Demchenko, V. Talanyuk, M. Iurzhenko, J. E. Puskas, and G. Adamus, Polymers, 12, Iss. 5: 1167 (2020); https://doi.org/10.3390/polym12051167
  6. Kathrina Lois M. Taaca, Eloise I. Prieto, and Magdaleno R. Vasquez, Jr., Polymers, 14: 2560 (2022); https://doi.org/10.3390/polym14132560
  7. Valeriy Demchenko, Yevgen Mamunya, Illia Sytnyk, Maksym Iurzhenko, Nataliia Rybalchenko, Svitlana Zahorodnia, Olena Demchenko, Stanislav Rushkovsky, Dmytro Kunytskyi, Donghu Zeng, Viktoriia Talaniuk, and Marta Musioł, ACS Applied Materials & Interfaces, 17, Iss. 38: 53312 (2025); https://doi.org/10.1021/acsami.5c14960
  8. G. Singh, A. Lohani, and S. Bhattacharya, Journal of Fundamental Pharmaceutical Research, 2: 35 (2024).
  9. Valeriy Demchenko, Polina Zaremba, Nataliia Rybalchenko, Svitlana Zahorodnia, Liubov Artiukh, Taras Rybalchenko, Olena Demchenko, Illia Sytnyk, Donghu Zeng, Serhii Kobylinskyi, Lyudmila Goncharenko, and Maksym Iurzhenko, Scientific Reports, 15: Article No. 35087 (2025); https://doi.org/10.1038/s41598-025-18932-9
  10. Mohammad Taghi Khorasani, Alireza Joorabloo, Hassan Adeli, Zohreh Mansoori-Moghadam, and Armaghan Moghaddam, Carbohydrate Polymers, 207: 542 (2019); https://doi.org/10.1016/j.carbpol.2018.12.021
  11. A. S. Montaser, Mohamed Rehan, Mehrez E. El-Naggar, International Journal of Biological Macromolecules, 124: 1016 (2019); https://doi.org/10.1016/j.ijbiomac.2018.11.252
  12. Amin Zeinali, Mohammad Sirousazar, Zeinab Hosseini Dastgerdi, and Farshad Kheiri, Journal of Macromolecular Science, B59: 263 (2020); https://doi.org/10.1080/00222348.2019.1709714
  13. Yang Liu, Ying Lv, Meiwen An, Fen Li, Ying Lu, and Jianbo Song, Journal of Macromolecular Science, B58: 634 (2019); https://doi.org/10.1080/00222348.2019.1615688
  14. Mohammad Taghi Khorasani, Alireza Joorabloo, Armaghan Moghaddam, Hamidreza Shamsi, and Zohreh Mansoori Moghadam, International Journal of Biological Macromolecules, 114: 1203 (2018); https://doi.org/10.1016/j.ijbiomac.2018.04.010
  15. Liubov Matkovska, Maksym Iurzhenko, Yevgen Mamunya, Olga Matkovska, Valeriy Demchenko, Eugene Lebedev, Gisele Boiteux, and Anatoli Serghei, Nanoscale Research Letters, 9: Article No. 674 (2014); https://doi.org/10.1186/1556-276X-9-674
  16. Ping Liu, Wenhua Chen, Cuihua Liu, Ming Tian, and Pengju Liu, Scientific Reports, 9: Article No. 9534 (2019); https://doi.org/10.1038/s41598-019-46061-7
  17. Anatoliy Galchun, Nikolay Korab, Volodymyr Kondratenko, Valeriy Demchenko, Andriy Shadrin, Vitaliy Anistratenko, and Maksym Iurzhenko, Nanoscale Research Letters, 10: Article No. 138 (2015); https://doi.org/10.1186/s11671-015-0832-4
  18. Divya Dharmaraj, Madhuri Krishnamoorthy, Kumar Rajendran, Kannan Karuppiah, Jeyameenakshi Annamalai, Karthick Rajan Durairaj, Prakash Santhiyagu, and Kannapiran Ethiraj, Journal of Drug Delivery Science and Technology, 61: 102111 (2020); https://doi.org/10.1016/j.jddst.2020.102111